
Fertility Center
GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute
Services Offered
About
GREFI (Gynecology, Reproductive Endocrinology & Fertility Institute) is a private fertility practice in Puerto Rico founded in 1991 by Rosa Ileana Cruz Burgos, MD, who continues to lead it. Dr. Cruz graduated from the University of Puerto Rico School of Medicine, trained in obstetrics and gynecology, and completed a fellowship in reproductive endocrinology and infertility at Rutgers Medical School in New Jersey.
The main office is in the First Bank Building at 1519 Ponce de León Avenue in Santurce, San Juan. Directory listings also show a second office in Coto Laurel, Ponce, serving patients in southern Puerto Rico.
Listed services include IUI, IVF with ICSI, preimplantation genetic testing, egg and embryo freezing, donor egg and donor sperm treatment, and gestational carrier cycles, as well as laparoscopic reproductive surgery and treatment of endometriosis and fibroids. The clinic is an affiliate of the MyEggBank frozen donor egg network.
IVF Success Rates
CDC 2022 data — the most recent final figures published
Own Eggs
Live birth rate per intended egg retrieval
| Age Group | This Clinic | National |
|---|---|---|
| <35 | 26.3% | 49.7% |
| 35-37 | 16.0% | 36.3% |
| 38-40 | 9.7% | 23.1% |
| >40 | 0.0% | 7.7% |
Sample: 134 cycles at this clinic
Three-year trend
Overall figures only — CDC publishes the diagnosis breakdown for 2022 alone.
| Age Group | 2021 | 2022 |
|---|---|---|
| <35 | 18.2% | 26.3% |
| 35-37 | — | 16.0% |
| 38-40 | 10.7% | 9.7% |
| >40 | — | 0.0% |
Success rates depend heavily on which patients a clinic accepts, so these numbers should not be used to rank clinics against one another. Cells CDC suppressed for small sample sizes (1-4 cycles) are shown as a dash.
Medical Team
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Similar Fertility Centers Nearby
All in PR →First Bank Building, 1519 Ponce de León Ave, Suite 705, San Juan, PR
Google MapsContact
First Bank Building, 1519 Ponce de León Ave, Suite 705, San Juan, PR, 00909
Clinic Info
Founded
1991
Medical Director
Rosa Ileana Cruz, MD
Annual Cycles
155