
Fertility Center
Pacific Fertility Center
Services Offered
About
Pacific Fertility Center (PFC) has served Northern California patients since 1999, when several reproductive endocrinologists merged their practices under the PFC name. In 2017 it joined The Prelude Network, the clinic network now operated by Inception Fertility.
The San Francisco clinic is at 55 Francisco Street, near Fisherman's Wharf, and PFC also runs an office in Greenbrae, Marin County. Physicians currently listed for the San Francisco site include Drs. Isabelle Ryan, Liyun Li, Michael Strug and Jennifer Agard. Embryologist Dr. Joseph Conaghan directs the clinical laboratory. PFC was an early adopter of egg vitrification and single embryo transfer. Its in-house Pacific Fertility Egg Bank is described as Northern California's first frozen donor egg program.
Services include fertility testing, IUI, IVF with ICSI, PGT, egg freezing and fertility preservation, egg donation, donor sperm, gestational surrogacy, male infertility care, and LGBTQ+ and single-parent family building. Out-of-town and international patients have support from new-patient coordinators. Chinese-speaking patients can see Shanghai-born Dr. Li, whose nursing team speaks Mandarin and Cantonese, and use a Chinese concierge service.
IVF Success Rates
CDC 2022 data — the most recent final figures published
Own Eggs
Live birth rate per intended egg retrieval
| Age Group | This Clinic | National |
|---|---|---|
| <35 | 39.6% | 49.7% |
| 35-37 | 38.3% | 36.3% |
| 38-40 | 26.4% | 23.1% |
| >40 | 10.0% | 7.7% |
Sample: 487 cycles at this clinic
Donor Eggs
Live birth rate per embryo transfer
| Egg / Embryo Type | This Clinic | National |
|---|---|---|
| Fresh embryo, fresh egg | — | 52.0% |
| Fresh embryo, frozen egg | — | 45.2% |
| Frozen embryo | 41.3% | 45.1% |
| Donated embryo | — | 42.2% |
Sample: 163 cycles at this clinic
Three-year trend
Overall figures only — CDC publishes the diagnosis breakdown for 2022 alone.
| Age Group | 2020 | 2021 | 2022 |
|---|---|---|---|
| <35 | 49.0% | 46.9% | 39.6% |
| 35-37 | 35.1% | 34.0% | 38.3% |
| 38-40 | 17.7% | 21.8% | 26.4% |
| >40 | 4.2% | 8.3% | 10.0% |
Success rates depend heavily on which patients a clinic accepts, so these numbers should not be used to rank clinics against one another. Cells CDC suppressed for small sample sizes (1-4 cycles) are shown as a dash.
Medical Team
Carolyn GivensMD
Obstetrics & Gynecology, Reproductive Endocrinology

Isabelle RyanMD
Obstetrics & Gynecology, Reproductive Endocrinology
medical director

Jennifer A. AgardMD

Liyun LiMD
Obstetrics & Gynecology, Reproductive Endocrinology
Michael StrugDO
Obstetrics & Gynecology, Reproductive Endocrinology
Philip ChenetteMD
Obstetrics & Gynecology, Reproductive Endocrinology
Reviews
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55 Francisco St, Suite 500, San Francisco, CA
Google MapsClinic Info
Founded
1999
Part of
Inception Fertility
Medical Director
Isabelle Ryan, MD
Chinese-speaking Staff
Available
Annual Cycles
1,792